11 research outputs found
Neutrino mixing matrices with relatively large and with texture one-zero
The recent T2K, MINOS and Double Chooz oscillation data hint a relatively
large , which can be accommodated by some general modification of
the Tribimaximal/Bimaximal/Democratic mixing matrices. Using such matrices we
analyze several Majorana mass matrices with texture one-zero and show whether
they satisfy normal or inverted mass hierarchy and phenomenologically viable or
not.Comment: 16 pages, 3 figures, minor modification in the text, version to
appear in EPJ
Development of a core outcome set for congenital pulmonary airway malformations: study protocol of an international Delphi survey
Introduction A worldwide lack of consensus exists on the optimal management of asymptomatic congenital pulmonary airway malformation (CPAM) even though the incidence is increasing. Either a surgical resection is performed or a wait-and-see policy is employed, depending on the treating physician. Management is largely based on expert opinion and scientific evidence is scarce. Wide variations in outcome measures are seen between studies making comparison difficult thus highlighting the lack of universal consensus in outcome measures as well. We aim to define a core outcome set which will include the most important core outcome parameters for paediatric patients with an asymptomatic CPAM.Methods and analysis This study will include a critical appraisal of the current literature followed by a three-stage Delphi process with two stakeholder groups. One surgical group including paediatric as well as thoracic surgeons, and a non-surgeon group including paediatric pulmonologists, intensive care and neonatal specialists. All participants will score outcome parameters according to their level of importance and the most important parameters will be determined by consensus.Ethics and dissemination Electronic informed consent will be obtained from all participants. Ethical approval is not required. After the core outcome set has been defined, we intend to design an international randomised controlled trial: the COllaborative Neonatal NEtwork for the first CPAM Trial, which will be aimed at determining the optimal management of patients with asymptomatic CPAM